Which statement explains why Pepto-Bismol is contraindicated in suspected Reye's syndrome?

Which statement explains why Pepto-Bismol is contraindicated in suspected Reye's syndrome?

• A. It contains acetaminophen
• B. It contains aspirin
• C. It contains ibuprofen
• D. It contains caffeine

Answer: (B)

Aspirin-like substances in Pepto-Bismol raise the risk of Reye’s syndrome when given during a viral illness. Pepto-Bismol contains bismuth subsalicylate, which is metabolized to salicylate—an aspirin-like compound. In children with viral infections, salicylates have been linked to the development of Reye’s syndrome, a dangerous condition affecting the liver and brain. Because of this, Pepto-Bismol is contraindicated if Reye’s syndrome is suspected. The other listed substances do not carry that same aspirin-related risk.

Aspirin-like substances in Pepto-Bismol raise the risk of Reye’s syndrome when given during a viral illness. Pepto-Bismol contains bismuth subsalicylate, which is metabolized to salicylate—an aspirin-like compound. In children with viral infections, salicylates have been linked to the development of Reye’s syndrome, a dangerous condition affecting the liver and brain. Because of this, Pepto-Bismol is contraindicated if Reye’s syndrome is suspected. The other listed substances do not carry that same aspirin-related risk.